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Accolate

Brand Names

; Accolate®

Leukotriene Receptor Antagonist

This medicine is used in the prevention and long-term treatment of asthma. It is not for the immediate (urgent) treatment of an asthma attack.

Zafirlukast decreases the body's production of a group of chemicals called leukotrienes that worsen asthma.

Take a missed dose as soon as possible.
If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
Do not take a double dose or extra doses.
Do not change dose or stop taking medicine without talking with healthcare provider.

Check medicines with healthcare provider. This medicine may not mix well with other medicines. Erythromycin and theophylline may decrease medicine's effect.
Wear disease medical alert identification for asthma.
Use caution with aspirin and aspirin-containing products. Side effects of these medicines may be increased.
If you are on warfarin (blood thinner) you will require more frequent monitoring if this medicine is added.
Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
Tell healthcare provider if you are pregnant or plan on getting pregnant.
Do not use if you are breast-feeding.

Headache. Mild pain medicine may help.
Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
Diarrhea.
Belly pain and cramps.
Rarely, liver disease may occur.

Check prothrombin time/INR if you are on warfarin. Talk with healthcare provider.
Follow up with healthcare provider.

Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
Severe nausea, vomiting, and/or diarrhea.
Nausea, vomiting, belly pain, itchy, flu-like feeling, feeling tired, dark urine, yellow eyes or skin, not hungry.
Any rash.
No improvement in condition or feeling worse.

Store in the original container at room temperature. Protect from light and moisture.

Do not share your medicine with others and do not take anyone else's medicine.
Keep all medicine out of the reach of children and pets.
Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).