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Ticlopidine

Brand Names

; Ticlid®

Antiplatelet Agent

Ticlopidine can decrease some of the important cells in the blood. You will need blood work to monitor these cells twice a month.

If you have an allergy to ticlopidine or any other part of the medicine.
If you have any of the following conditions: Active bleeding, severe liver disease, any diseases of the blood or bone marrow, abnormalities in any of the cells in your blood, aplastic anemia, thrombotic thrombocytopenic purpura, low neutrophil count, low platelet count.

This medicine prevents strokes.
Other uses include protection of bypass grafts in the heart, protection of stents in the heart, reduction of graft loss after kidney transplant, and prevention of blood clots.

Take with or without food. Take with food if this medicine causes an upset stomach.

Take a missed dose as soon as possible.
If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
Do not take a double dose or extra doses.

If you are 65 or older, you may have more side effects.
Tell healthcare provider if you have ever had a blood problem or low blood counts.
Tell healthcare provider if you are taking phenytoin, cyclosporine, or theophylline. These medicines may need to be decreased.
If you have had a stomach ulcer or bleeding, tell healthcare provider.
You will bleed easily. Be careful. Avoid injury.
Tell dentists, surgeons, and other healthcare providers about this medicine.
Avoid other aspirin-containing products, such as, ibuprofen or like products, other blood thinners (warfarin, ticlopidine, clopidogrel), garlic, ginseng, ginkgo, vitamin E.
Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
Do not use in pregnancy and do not get pregnant. Use birth control that you can trust while taking this medicine.
Do not use if you are breast-feeding.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
Diarrhea.
Belly pain, heartburn.
Stomach bleeding or ulceration. Watch stools for dark, tarry black color. Talk with healthcare provider.
Rarely, decreases in white blood cell, red blood cells, and platelets can occur together. This condition is called aplastic anemia and can cause death.
Rarely, decreases in platelets can occur. This condition is call thrombocytopenia.

Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
Fever, chills, or sore throat.
Changes in thinking clearly and logically.
Severe headache.
Blood in the stool and toilet bowl or vomiting blood.
Weakness, feeling tired, paleness, bruising, bleeding, difficulty speaking, yellowing of skin or eyes, dark or bloody urine, or pinpoint hemorrhage spots on the skin (petechiae).
Any rash.
No improvement in condition or feeling worse.

Do not share your medicine with others and do not take anyone else's medicine.
Keep all medicine out of the reach of children and pets.
Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).