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Nateglinide
Brand Names
; Starlix®Therapeutic Categories
Antidiabetic AgentReasons not to take this medicine
- If you have an allergy to nateglinide or any other part of the medicine.
- If you have type 1 diabetes or insulin dependent diabetes.
- If you have had an acid condition in the blood called diabetic ketoacidosis.
What is this medicine used for?
- This medicine is used to lower blood sugar in diabetic patients. It is used in type 2 or non-insulin dependent diabetes. It can be used alone or in combination with another diabetes medicine called metformin.
How does it work?
- Nateglinide increases insulin secretion from the pancreas. The pancreas makes insulin. The insulin helps the body handle and use the sugar in the blood after a meal.
How is it best taken?
- Take 1-30 minutes before each meal (breakfast, lunch, and dinner).
- If a meal is missed then skip that dose too.
- Follow diet plan and exercise program as recommended by healthcare provider.
What do I do if I miss a dose?
- If you miss a dose then skip the missed one. Return to your regular schedule.
- Do not take a double dose or extra doses.
- Do not change dose or stop taking medicine without talking with healthcare provider.
What are the precautions when taking this medicine?
- Wear disease medical alert identification for diabetes.
- If you have been taking a medicine called a sulfonylurea for diabetes tell your healthcare provider. Some examples include glyburide, glipizide, and glimepiride. Patients on a sulfonylurea do not get any extra benefit by adding nateglinide.
- Certain medicines may increase your blood sugar and certain ones may increase the risk of developing very low blood sugars. Talk with healthcare provider.
- If you are 80 years of age or older, you may be more sensitive to low blood sugars.
- Avoid alcohol (includes wine, beer, and liquor).
- Keep hard candies, liquid glucose, or milk on hand for low blood sugars.
- Do not drive if blood sugar has been low. There is a greater risk of an accident.
- Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
- Tell healthcare provider if you are pregnant or plan on getting pregnant.
- Tell healthcare provider if you are breast-feeding.
What are the common side effects of this medicine?
- Lung infections.
- Back pain.
- Dizziness. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
- Flu-like symptoms.
- Weight gain.
What should I monitor?
- Check blood sugar as ordered by healthcare provider. Call if glucose is less than 80 mg/dL or greater than 250 mg/dL. Bring results to follow-up visits.
- Watch for low blood sugar. Causes anger, shaking, rapid heartbeats, confusion, sweating.
- Watch for high blood sugar. Causes many trips to the bathroom, thirst, and weight loss.
- Check blood work. Talk with healthcare provider.
- Weight.
- Have a yearly eye exam and visit to the foot doctor.
Reasons to call healthcare provider immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, throat.
- Signs and symptoms of infection.
- Low blood sugar or very high blood sugar.
- Any rash.
How should I store this medicine?
- Store at room temperature.
General statements
- Do not share your medicine with others and do not take anyone else's medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).






