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Kaletra
Brand Names
; Kaletra™Therapeutic Categories
Antiretroviral Agent, Reverse Transcriptase Inhibitor (Non-Nucleoside)Reasons not to take this medicine
- If you have an allergy to lopinavir, ritonavir, or any other part of the medicine.
- If you are taking any of these medicines: Flecainide, propafenone, astemizole, terfenadine, midazolam, triazolam, cisapride, dihydroergotamine, ergonovine, ergotamine, methylergonovine, pimozide.
What is this medicine used for?
- This medicine is used to treat HIV infection. It is usually taken with other medicines.
How does it work?
- Lopinavir stops the HIV virus from increasing. It binds up an enzyme that is needed for reproduction of the virus.
- Ritonavir increases the levels of lopinavir in the blood.
How is it best taken?
- To gain the most benefit, do not miss doses.
- Take with food.
- Swallow capsule whole. Do not chew, break, or crush.
- A liquid (solution) is available for patients who cannot swallow pills.
What do I do if I miss a dose?
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
- Do not take a double dose or extra doses.
- Do not change dose or stop taking medicine without talking with healthcare provider.
What are the precautions when taking this medicine?
- Use caution if you have hemophilia. Some patients have increased bleeding.
- Use caution if you have had pancreatitis. Talk with healthcare provider.
- Use caution if you have diabetes. Your blood sugars may increase. Watch closely.
- Use caution if you have liver disease. Talk with healthcare provider.
- Check medicines with healthcare provider. This medicine may not mix well with other medicines.
- Do not take this medicine with St. John's wort.
- Do not run out of this medication. Get it refilled today!
- Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
- Protect against sexual spread of disease. Use an effective method of birth control. Talk with healthcare provider if you have questions.
- Birth control pills do not protect against the spread of sexual diseases. In addition, birth control pills may not work very well to prevent pregnancy with this medicine.
- Breast-feeding is not recommended in HIV disease.
What are the common side effects of this medicine?
- Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
- Diarrhea.
- Increased cholesterol and triglyceride levels in the blood. Levels should be checked before starting medicine.
- Headache.
- Weakness or feeling tired.
- Changes in body fat. Increased fat in upper back, neck, chest and belly areas. Decreased fat in arms, legs and face may occur.
What should I monitor?
- Check blood work. Talk with healthcare provider.
- If you are diabetic, follow blood glucose levels closely. You may see an increase in levels.
- Follow up with healthcare provider.
Reasons to call healthcare provider immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, throat.
- Nausea, vomiting, or belly pain.
- Any rash.
- No improvement in condition or feeling worse.
How should I store this medicine?
- Store in the refrigerator. Protect from excessive heat.
- Can store at room temperature but must use within 2 months.
General statements
- Do not share your medicine with others and do not take anyone else's medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).






