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Sinemet

Brand Names

; Sinemet® ; Sinemet® CR

; Racovel (Mexico)

Anti-Parkinson's Agent (Dopamine Agonist)

If you have an allergy to carbidopa, levodopa, or any other part of the medicine.
If you have any of the following conditions: Narrow-angle glaucoma, history of melanoma, unexplained skin spots.
If you have taken a monoamine oxidase inhibitor (phenelzine, tranylcypromine, isocarboxazid) in the last 14 days.

When used in Parkinson's disease, it improves the chemical balance in the brain.

Take with or without food. Take with food if this medicine causes an upset stomach.
Swallow sustained-release tablet whole or as a half. Do not crush or chew.
Avoid high protein diets.

Take a missed dose as soon as possible.
If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
Do not take a double dose or extra doses.
Do not change dose or stop taking medicine without talking with healthcare provider.
Separate sustained-release dose by at least 6 hours.

If you are 65 or older, you may have more side effects.
You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
Avoid alcohol (includes wine, beer, and liquor) and other medicines and herbs that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider.
Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
Tell healthcare provider if you are pregnant or plan on getting pregnant.
Tell healthcare provider if you are breast-feeding.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
Lightheaded. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.
Involuntary movements. Twitching; twisting moves or repeated movement of face, legs, or arms.

Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
Changes in balance, feeling shaky or unsteady.
Changes in thinking clearly and logically.
Severe nausea, vomiting, or diarrhea.
Involuntary movements.
Any rash.
No improvement in condition or feeling worse.

Do not share your medicine with others and do not take anyone else's medicine.
Keep all medicine out of the reach of children and pets.
Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).