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TACE

Brand Names

; TACE®

Estrogen Derivative

If you have an allergy to chlorotrianisene or any other part of the medicine.
If you have any of the following conditions: Thrombophlebitis, breast cancer, abnormal vaginal bleeding.
If you are pregnant or think you may be pregnant.

This medicine is used to stop/reduce the symptoms of menopause, especially hot flashes, vaginal dryness, itching, and burning.
It is used to treat female hypogonadism.
Rarely, it is used for the treatment of prostate cancer.

After menopause, when the body no longer produces estrogen, chlorotrianisene is used as a simple replacement of estrogen.

Take with food at a similar time every day or as directed by your healthcare provider. There may be days when you will not take the medicine.

Take a missed dose as soon as possible.
If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
Do not take a double dose or extra doses.
Do not change dose or stop taking medicine without talking with healthcare provider.

This medicine does not treat depression or nervous problems.
Limit alcohol intake (includes wine, beer, and liquor). May increase risk of breast cancer.
Do not use if you have unusual vaginal bleeding that has not been examined by healthcare provider.
Use caution if you have a weakened heart or high blood pressure. Talk with healthcare provider.
Tell your healthcare provider if you have ever had any blood clots in your legs, arms, or lungs.
There may be a higher risk of endometrial/breast cancer. Talk with healthcare provider.
Do not use if you have had breast or uterine cancer or if someone in your family (sister, mother) has had breast cancer. Talk with healthcare provider.
Do not take if allergic to the dye tartrazine (yellow). This is seen more often in people allergic to aspirin.
Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
Do not use in pregnancy and do not get pregnant. Use birth control that you can trust during use of this medicine and for 1 month after stopping it.
Do not use if you are breast-feeding.

Headache. Mild pain medicine may help.
Belly pain and cramps.
Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
Breast enlargement/tenderness.
For women, vaginal bleeding (breakthrough bleeding, spotting) may occur.
Change in sexual ability or desire. This can return to normal after medicine is stopped. Talk with healthcare provider about other medicines without this side effect.

For women, periodic breast (monthly self-exams) and gynecologic exams are important.
Follow diet plan (calcium and vitamin D supplementation) and exercise program as recommended by healthcare provider.
Follow up with healthcare provider at least every year. Talk about duration of treatment.

Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
Severe headache.
For women, unusual vaginal bleeding. This includes lots of bleeding, spotting, or bleeding between cycles.
Severe nausea, vomiting, and/or diarrhea.
Any rash.
Swelling/pain of a leg or arm, sudden shortness of breath, difficulty breathing, chest pain.
A lump in the breast.
Any rash.

Do not share your medicine with others and do not take anyone else's medicine.
Keep all medicine out of the reach of children and pets.
Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
Read the package insert for more details (given with the medicine).
Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).