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Amiloride
Brand Names
; Midamor®Therapeutic Categories
Diuretic, Potassium SparingReasons not to take this medicine
- If you have an allergy to amiloride or any other part of the medicine.
- If you have any of the following conditions: High potassium levels in the blood, severe kidney disease, kidney disease caused by diabetes.
- If you have kidney disease or diabetes you need to be watched closely.
- If you are taking other potassium-conserving agents (eg, spironolactone, triamterene) or potassium supplementation (medicine, potassium-containing salt substitutes, potassium-rich diet).
What is this medicine used for?
- This medicine is used to get rid of extra fluid, salt, and water slowly and gently.
- It is frequently used in a liver disease called cirrhosis.
- It can also be used to increase potassium stores in the body.
How does it work?
- Amiloride can get rid of extra salt and water in the body. It competes against a hormone made in the body called aldosterone. In the same way, amiloride increases potassium stores in the body.
How is it best taken?
- Take with or without food. Take with food if this medicine causes an upset stomach.
- Follow diet plan (low sodium) as recommended by healthcare provider.
- Tablet may be crushed and mixed with food or liquid.
What do I do if I miss a dose?
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
- Do not take a double dose or extra doses.
What are the precautions when taking this medicine?
- Check medicines with healthcare provider. Make sure other medicines you are taking do not increase potassium.
- Avoid alcohol (includes wine, beer, and liquor). Can increase weight gain.
- Not for use in kidney disease. Talk with healthcare provider.
- Do not use over-the-counter products that increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain herbs or supplements. Talk with healthcare provider.
- Avoid potassium-containing salt substitutes and potassium supplements. Talk with healthcare provider.
- Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
- Tell healthcare provider if you are pregnant or plan on getting pregnant.
- Tell healthcare provider if you are breast-feeding.
What are the common side effects of this medicine?
- Feeling lightheaded. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
- Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.
- Females: Breast tenderness, deepening of voice, increased hair growth, menstrual changes.
- Males: Breast enlargement.
- Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
- High potassium. This may make you feel weak, lightheaded, dizzy, or have numbness and tingling.
- Change in sexual ability or desire. This can return to normal after medicine is stopped. Talk with healthcare provider about other medicines without this side effect.
What should I monitor?
- If you are using this medicine for fluid removal, check daily weight. Report a weight gain or no weight loss.
- Check blood pressure regularly.
- Follow diet plan (low salt) and exercise program as recommended by healthcare provider.
- Check blood work. Talk with healthcare provider.
Reasons to call healthcare provider immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
- Passing out, fainting, dizziness, lightheadedness, weakness, numbness, and tingling.
- Severe nausea, vomiting, and/or diarrhea.
- Menstrual changes. This includes lots of bleeding, spotting, or bleeding between cycles.
- Any rash.
How should I store this medicine?
- Store in a tight container at room temperature. Protect from moisture, freezing, and excessive heat.
General statements
- Do not share your medicine with others and do not take anyone else's medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).






